C&O Canal 100

APR

25

2026

Run 100 miles along the scenic C&O Canal towpath on April 25, 2026, with sweeping Potomac River and Appalachian views. Low elevation, smooth terrain and friendly aid stations make this WSER qualifier a spring ultramarathon.

Sat 25 Apr 2026

Knoxville, Maryland

Website Registration

100 miles

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C&O Canal 100 - Knoxville, MD

The C&O Canal 100 is a 100-mile ultramarathon held on April 25, 2026, in Knoxville, Maryland, with the event base at Camp Manidokan, 1600 Harpers Ferry Rd. The race is listed as a WSER 2026 qualifier. Registration opens January 1, 2026. The course runs between Antietam and Brunswick, MD, along the C&O Canal towpath and follows the Potomac River with views of the Appalachian mountains.

Course and logistics

The course layout is one approximately 40-mile loop followed by two approximately 30-mile loops.

40-mile loop
30-mile loop
30-mile loop

There will be about seven aid stations placed throughout each loop, some encountered multiple times. Distances between aid stations range from 3 to 6.9 miles. The course is described as having low elevation and smooth terrain and is held in spring, when weather is typically temperate. Volunteers will staff aid stations and support runners along the towpath. Visit the organization's website for the most recent information.

100 mi

100 Miles