C&O Canal 100

APR

25

2026

Run 100 miles along the scenic C&O Canal towpath on April 25, 2026 near Knoxville, Maryland, with river and Appalachian views and helpful aid stations along the route. This spring ultramarathon is a WSER 2026 qualifier.

Sat 25 Apr 2026

Knoxville, Maryland

Website Registration

100 miles

Always double-check with the organizer's website! This page may contain affiliate links.

Event

The C&O Canal 100 is a 100 miles ultramarathon scheduled for April 25, 2026 in Knoxville, Maryland. Registration opens January 1, 2026. The race is a WSER 2026 qualifier.

Course and support

The course uses the historic C&O Canal towpath along the Potomac River and runs between Antietam and Brunswick, MD. The race starts at Camp Manidokan and consists of one ~40-mile loop followed by two ~30-mile loops, with nearly every mile close to the river and the Appalachian mountains.

There are approximately seven aid stations placed throughout each loop, some of which are encountered multiple times. Distances between aid stations range from 3-6.9 miles. The course is described as having low elevation and smooth terrain and takes place in spring conditions. Organizers provide volunteers and stocked aid stations along the route. Visit the organization's website for the most recent information.

100 mi

100 Miler