Run Across Tennessee 170 Mile Relay

JUN
5
2026
Join a 170 mile team relay from the Virginia border to the Georgia line to support rare disease research. Navigate through Eastern Tennessee in this unique adventure where timing and teamwork are key to finishing together.
Fri 5 Jun 2026
170 miles

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Run Across Tennessee Relay

The Run Across Tennessee Relay is a team-based event covering a distance of 170 miles. The course begins at the Tennessee-Virginia state line north of Harrogate and proceeds south through Knoxville. The route concludes at the Tennessee-Georgia state line south of Cleveland, Tennessee.

This event functions as a fundraiser to support research and treatment for NGLY1 deficiency. It is organized as an informal adventure rather than a traditional race. Participants are responsible for their own transportation, lodging, food, water, and general safety.

The relay uses a specific timing format where teams choose their own start time between Friday and Sunday. The objective is to finish the course as close to 3:00pm on Sunday as possible. A penalty of one hour is applied for every minute a team finishes outside of the 2:55pm to 3:00pm grace period. This structure allows various teams to arrive at the finish line simultaneously to walk across the state line together.

Safety requirements are mandatory for all participants. Runners must wear high-visibility vests at all times and light-up vests during night sections. Because the course roads remain open to commercial traffic, two specific sections of the route must be skipped by all teams due to a lack of road shoulders. Visit the organization's website for the most recent information.

  • 170 Mile Relay
170 mi
170 Mile Relay